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Hi, decided to go for treatment. Chemo (carboplatin) immuno (Keytruda) and (Denosumab (for bone protection). She mentioned how it was for two years then a break and could go back on it if working. Mind you reading the sheets of side effects it’s scary! Got to try. Have been offered lots of support by team so we shall see. Would be interested in anyone on these drugs. Starting after Xmas

December 18, 2025
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A MyLungCancerTeam Member

It says on my forms it is?

December 19, 2025
A MyLungCancerTeam Member

Greetings Tina!
The carboplatin probably isn't for a year. Check with your doctor or infusion nurse.
I've had carboplatin twice. The first time in 2020 was in conjunction with radiotherapy when I had 1 infusion per week for 8 weeks. I had no side effects from it. I didn't lose any hair.

The second time was in 2022 as one half of the chemo cocktail that I was given every 3 weeks for 4 cycles (infusions). The other chemo agent was Taxol, which did severely affect me. I also started my immunotherapy of Keytruda at the same time.

After I was off of chemotherapy and only receiving Keytruda, I experienced an ongoing itchy, bumpy rash and daily fatigue. I did 2 years on Keytruda and now, 15 months after stopping, I still have the rash and fatigue.

I have a prescription for Triamcinolone Cream for the rash and also use Eucerin Cream as well. They work well and if I use them daily.

The fatigue is nothing that stops me from doing what I want to do, but just enough excuse to not do what I don't care to do. : )

Stay positive!
Tony

December 19, 2025
MyLungCancerTeam

What are the side effects of carboplatin, Keytruda, and denosumab for lung cancer treatment?

It's completely understandable to feel overwhelmed by those side effect sheets—they can be scary! The good news is that your team is offering lots of support, which makes a real difference.

For Keytruda (pembrolizumab), common Show Full Answer

What are the side effects of carboplatin, Keytruda, and denosumab for lung cancer treatment?

It's completely understandable to feel overwhelmed by those side effect sheets—they can be scary! The good news is that your team is offering lots of support, which makes a real difference.

For Keytruda (pembrolizumab), common side effects include:
* Fever
* Nausea and fatigue
* Loss of appetite
* Itching or skin rash
* Joint pain
* Diarrhea and headache
* High or low blood pressure

Since it's given through an IV, you might experience infusion reactions like chills, flushing, or dizziness. Let your nurse know immediately if you feel anything unusual during infusion.

Carboplatin chemotherapy can cause:
* Weakness or fatigue
* Nausea and vomiting
* Hair loss
* Decreased blood cell counts (leading to higher infection risk or bruising)
* Mouth sores
* Diarrhea or constipation

Your team will monitor your blood counts closely and can prescribe medications to help manage nausea and other symptoms.

Regarding denosumab and dental concerns: While the search results don't specifically address denosumab's dental side effects, it's important to discuss this with your oncology team. Before starting treatment, visiting a dentist for a cleaning and checkup can help prevent complications. Good oral hygiene during treatment is crucial.

Many side effects are manageable with medications and support. Stay open with your team about what you're experiencing—your quality of life matters!

December 18, 2025

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