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Real members of MyLungCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
November 13, 2025
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A MyLungCancerTeam Member

I stopped after 25 infusions over 2 years of treatment. I started seeing new nodules on my PET/CT scans in the last 6 months of the treatment. Now 1 year after stopping, the nodules appear and disappear, grow and shrink, so it appears the Keytruda is still helping. The VA pretty much limits the treatment to 2 years, which is a common practice. There was a study done by Penn Med that showed the overall survival rate wasn't much improved by staying in treatment beyond 2 years, while the rate of adverse events increased substantially if you stayed in treatment. Some of the adverse effects were irreversible and sometimes deadly. Though I have read about patients that stayed on it much longer with no problem. I argued to stay on it until I read that study. Sadly, the cost steers insurance companies to stop the treatment regardless of the doctor's or patient's desires.

November 14, 2025
A MyLungCancerTeam Member

I' ve been on Ketruda for 15 months every 21 days until Nov '26. At that point I'm hoping and praying  I'm in remission. Have to admit I'm tired of it and very fatigued.Good luck.Kittie DaySent from my T-Mobile 5G Device 
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November 13, 2025
A MyLungCancerTeam Member

Ty!

November 14, 2025
MyLungCancerTeam

How long do people typically continue Keytruda treatment for squamous NSCLC?

Keytruda treatment duration varies based on your specific situation and how well the treatment is working. The decision to continue or stop isn't typically based on a set number of treatments, but rather on:

* How well your cancer is responding
* Show Full Answer

How long do people typically continue Keytruda treatment for squamous NSCLC?

Keytruda treatment duration varies based on your specific situation and how well the treatment is working. The decision to continue or stop isn't typically based on a set number of treatments, but rather on:

* How well your cancer is responding
* Whether you're experiencing manageable side effects
* Your overall health status
* Whether your disease has progressed

Some people continue Keytruda as maintenance therapy to help prevent cancer from returning or progressing, while others may stop after completing their planned treatment course. Your oncologist will monitor your progress through regular scans and bloodwork to determine the best approach for you.

It's important to have an open conversation with your healthcare team about your specific treatment plan. They can explain whether continuing treatment makes sense in your case, discuss the potential benefits of maintenance therapy versus stopping, and address any concerns you have about side effects or quality of life.

Every person's cancer journey is unique, so what works for one person may be different for another.

November 13, 2025

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