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Real members of MyLungCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.

Are any of you on immunotherapy also taking antihistamines? I have been taking Claritin. Studies show may make immunotherapy work better.

A MyLungCancerTeam Member asked a question 💭
Canaan, NH
March 2, 2025
 · 
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Answer Summary

Members shared experiences with taking antihistamines alongside immunotherapy and targeted treatments, with many confirming their oncologists... Read more

Members shared experiences with taking antihistamines alongside immunotherapy and targeted treatments, with many confirming their oncologists actively recommended or approved using medications like Claritin, Allegra, and Benadryl to manage side effects such as itchy skin, runny nose, bone pain, and chemo nausea. Several members described positive outcomes, including reduced nausea, fewer treatment side effects, and belief in a synergistic effect that may enhance immunotherapy effectiveness, while others found antihistamines helpful primarily for managing persistent skin itchiness from targeted therapies. A recurring theme was the reassurance that doctors found no contraindications and even encouraged daily use, especially as allergy season approaches, with many members continuing antihistamines long after treatment ended.

A MyLungCancerTeam Member

I believe it must help at least with side effects because I took it and really didn't have issues during treatment.

March 3, 2025
A MyLungCancerTeam Member

I am on keyruda and also taking claritan. One of my side effects of keytruda is a runny nose. My Dr knows I'm taking it and I also have read there may be a synergistic effect. I hope so.

March 3, 2025
A MyLungCancerTeam Member

Interesting. I’ll have to ask my doctor about this

March 2, 2025
MyLungCancerTeam

While the search results don't specifically address antihistamines with immunotherapy, it's important to discuss any medications you're taking with your healthcare team. This includes over-the-counter medications like Claritin, as they could interact with your treatment.

Immunotherapy works by helping your immune system Show Full Answer

While the search results don't specifically address antihistamines with immunotherapy, it's important to discuss any medications you're taking with your healthcare team. This includes over-the-counter medications like Claritin, as they could interact with your treatment.

Immunotherapy works by helping your immune system recognize and fight cancer cells. Any medications that affect your immune system should be carefully evaluated by your doctor to ensure they don't interfere with your treatment. If you experience side effects from immunotherapy like itching or skin rash, which are common, make sure to let your healthcare team know. They can properly evaluate whether antihistamines are appropriate for managing these symptoms while maintaining the effectiveness of your immunotherapy treatment.

March 2, 2025
A MyLungCancerTeam Member

Yes helps a lot

March 7, 2025

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