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Real members of MyLungCancerTeam have posted questions and answers that support our community guidelines, and should not be taken as medical advice. Looking for the latest medically reviewed content by doctors and experts? Visit our resource section.
December 12, 2025
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A MyLungCancerTeam Member

IMFINZI is not part of Chemotherapy. It is considered for use as Immunitherapy for the treatment of NSCLC. Yes, there can be some serious side effects associated with its use. I would like to suggest you GOOGLE "IMFINZI" to learn more about this medication̈. I would also, strongly, suggest you speak to your Oncologist Hemotologist, Immunologist or Pharmacist to address any concerns. If you believe you may be having s2vere side effects from this medication. You would want to address them immediately with you Oncologist, etc.

December 12, 2025
A MyLungCancerTeam Member

These are the known side effects of all the immunotherapy treatments-and yes, they can be cumulative.

December 29, 2025
MyLungCancerTeam

Are the effects of Imfinzi cumulative, and will fatigue and aches worsen with continued treatment?

Chemotherapy effects can be cumulative and build up after each round, often making later treatments feel harder than earlier ones. However, Imfinzi (durvalumab) is an immunotherapy, not traditional chemotherapy, so it may Show Full Answer

Are the effects of Imfinzi cumulative, and will fatigue and aches worsen with continued treatment?

Chemotherapy effects can be cumulative and build up after each round, often making later treatments feel harder than earlier ones. However, Imfinzi (durvalumab) is an immunotherapy, not traditional chemotherapy, so it may work differently in your body.

Fatigue is a common side effect that many people experience during lung cancer treatment. It's good that prednisone is providing some relief - this suggests your care team is actively managing your symptoms.

Here are some important points to consider:

- Side effects can vary from person to person and may not necessarily worsen with each dose
- Your body may adjust to the treatment over time
- Fatigue and muscle aches are manageable symptoms that your doctor can help address
- Keeping a symptom diary can help your care team adjust your treatment plan if needed

Since you're already on dose 4 and prednisone is helping, continue communicating openly with your doctor about how you're feeling. They can adjust medications, modify dosages, or provide additional supportive care to keep you as comfortable as possible throughout treatment.

December 12, 2025

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